Successful matched-unrelated bone marrow transplantation in a patient with beta-thalassemia major

研究成果: Article同行評審

3 引文 斯高帕斯(Scopus)

摘要

The authors describe a 5-year-old boy with beta-thalassemia major who received bone marrow transplantation (BMT) from a human leukocyte antigen (HLA)-matched unrelated donor. The conditioning regimen consisted of 16 mg/kg busulfan and 200 mg/kg cyclophosphamide. The transplantation was complicated with grade II graft-versus-host disease, although prophylaxis with cyclosporine and short-term methotrexate was carried out. Cytomegalovirus disease occurred at 2 months after transplantation but was controlled successfully. The child remains disease-free and in good clinical condition 53 months after BMT. The authors suggest that BMT from an HLA-matched unrelated donor could be considered as an alternative treatment in patients with beta-thalassemia major when no HLA-matched donor is available.

原文English
頁(從 - 到)579-581
頁數3
期刊Journal of Pediatric Hematology/Oncology
24
發行號7
DOIs
出版狀態Published - 2002 十月

All Science Journal Classification (ASJC) codes

  • 兒科、圍產兒和兒童健康
  • 血液學
  • 腫瘤科

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