TY - GEN
T1 - Suction-type microfluidic immunomagnetic bead-based system for rapid detection of influenza infection
AU - Huang, Tze Bin
AU - Hung, Lien Yu
AU - Tsai, Yi Che
AU - Yeh, Chen Sheng
AU - Lei, Huan Yao
AU - Lee, Gwo Bin
PY - 2011/12/1
Y1 - 2011/12/1
N2 - Seasonal and novel influenza infections have caused worldwide pandemic. In order to properly treat the infected patients, a rapid and accurate influenza diagnostic tool should be developed. This study therefore presented a new integrated microfluidic system for detection of influenza infection. It integrated a suction-type, pneumatic-driven microfluidic control module, a magnetic bead-based fluorescent immunoassay (FIA) and an end-point optical detection module. This new system could successfully distinguish the influenza A and B within 15 minutes, respectively. Furthermore, the results from 40 patient specimens have concluded that 75% sensitivity and 75% specificity in both positive and negative detections. This developed system would provide a powerful platform for fast screening of influenza infection.
AB - Seasonal and novel influenza infections have caused worldwide pandemic. In order to properly treat the infected patients, a rapid and accurate influenza diagnostic tool should be developed. This study therefore presented a new integrated microfluidic system for detection of influenza infection. It integrated a suction-type, pneumatic-driven microfluidic control module, a magnetic bead-based fluorescent immunoassay (FIA) and an end-point optical detection module. This new system could successfully distinguish the influenza A and B within 15 minutes, respectively. Furthermore, the results from 40 patient specimens have concluded that 75% sensitivity and 75% specificity in both positive and negative detections. This developed system would provide a powerful platform for fast screening of influenza infection.
UR - http://www.scopus.com/inward/record.url?scp=84883825123&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883825123&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84883825123
SN - 9781618395955
T3 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
SP - 509
EP - 511
BT - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
T2 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Y2 - 2 October 2011 through 6 October 2011
ER -