Suspended rice particles for cultivation of Monascus purpureus in a tower-type bioreactor

W. T. Wu, P. M. Wang, Y. Y. Chang, T. K. Huang, Y. H. Chien

研究成果: Article同行評審

12 引文 斯高帕斯(Scopus)


Cultivation of Monascus purpureus (CCRC 31615) for the production of natural pigments was investigated. Traditionally, Monascus species were grown on rice by solid-state culture. For large-scale cultivation, solid-state cultures were associated with some problems such as contamination and scale- up. By using submerged cultures with rice particles, a stirred-tank fermentor was not suitable for submerged cultures as the impeller tended to break the particles into small pieces. A conventional bubble column was also unsuitable as its mixing capability was poor. In the present study, a modified bubble column with wire-mesh draft tubes was employed for the cultivation of M. purpureus. The proposed column had a shorter mixing time and a higher oxygen transfer rate relative to the conventional bubble column. The production of pigments using the proposed column was up to 80% higher than that achieved using the conventional bubble column.

頁(從 - 到)542-544
期刊Applied Microbiology and Biotechnology
出版狀態Published - 2000

All Science Journal Classification (ASJC) codes

  • 生物技術
  • 應用微生物與生物技術


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