Sequential window acquisition of all theoretical fragment ion spectra coupled to tandem mass spectrometry (SWATH-MS) is a new strategy for identification and quantification of proteins and proteomes proposed in 2012. SWATH-MS operates in unbiased data-independent acquisition (DIA) mode and combines the advantages of two widely used MS-based techniques: shotgun (high throughput) and SRM proteomics (high sensitivity and reproducibility). In this review, we provide an introduction of the SWATH-MS method, its application, and a perspective on the future of this powerful technology.
|頁（從 - 到）||192-202|
|期刊||International Journal of Computational Biology and Drug Design|
|出版狀態||Published - 2015|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Computer Science Applications