Sweet's syndrome in a severely neutropenic patient during therapy with recombinant human granulocyte colony-stimulating factor

Sheau Chiou Chao, J. Yu Yun Lee, Chao Jung Tsao

研究成果: Article同行評審

7 引文 斯高帕斯(Scopus)

摘要

We report a new case of Sweet's syndrome (SS) associated with recombinant human granulocyte colony-stimulating factor (rHuG-CSF) therapy in a patient with acute myelogenous leukemia (AML). The patient developed a fever in association with multiple tender, purpuric and pustular skin lesions and swelling of both calves alter receiving rHuG-CSF 3 μg/kg/d for 4 days. The absolute neutrophil count was 0.55 x 109/L at onset. A skin biopsy revealed a dense neutrophilic infiltration in the dermis without evidence of vasculitis or infection. All skin and calf lesions regressed within 1 week after prednisolone therapy. Physicians should be aware of potential neutrophil-mediated dermatoses in patients with severe neutropenia on rHuG-CSF treatment.

原文English
頁(從 - 到)276-279
頁數4
期刊Journal of the Formosan Medical Association
96
發行號4
出版狀態Published - 1997 四月 1

All Science Journal Classification (ASJC) codes

  • 醫藥 (全部)

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