TY - JOUR
T1 - Synthesis High Sensivity ZnO Cholesterol Biosensor with One Dimensional Nanostructures
AU - Lu, Y. M.
AU - Jhuang, P. G.
AU - Tang, J. F.
AU - Chu, S. Y.
AU - Hsu, Cw
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2016/6/6
Y1 - 2016/6/6
N2 - Chelosterol ZnO biosensors were synthesized by hydrothermal method with predeposited ALD-ZnO seed layers. The ZnO nanostructures were examined by SEM, XRD, AFM, respectively. The XRD is used to analyze the crystal structures of ZnO seed layers that were grown by ALD process, then using SEM and AFM to analysis the surface morphologies of them. Growing of one dimensional ZnO nanostructures on seed layer of 10nm thickness, reveals high sensitivity of 3.15 uA (mg/dl)-1cm-2(121.96 uAmM-1cm-2) and low Km value of 29mM in 25-100mg/dl cholesterol concentration range. The response time could be as low as 10seconds. In the study, it is found that increasing the aspect ratio of ZnO one dimensional nanostructure also increases the sensitivity and expends the linear measureable range of detecting cholesterol in solution. The thickness of seed layer has a significant influence on sensitivity for one dimensional nano ZnO cholesterol biosensor.
AB - Chelosterol ZnO biosensors were synthesized by hydrothermal method with predeposited ALD-ZnO seed layers. The ZnO nanostructures were examined by SEM, XRD, AFM, respectively. The XRD is used to analyze the crystal structures of ZnO seed layers that were grown by ALD process, then using SEM and AFM to analysis the surface morphologies of them. Growing of one dimensional ZnO nanostructures on seed layer of 10nm thickness, reveals high sensitivity of 3.15 uA (mg/dl)-1cm-2(121.96 uAmM-1cm-2) and low Km value of 29mM in 25-100mg/dl cholesterol concentration range. The response time could be as low as 10seconds. In the study, it is found that increasing the aspect ratio of ZnO one dimensional nanostructure also increases the sensitivity and expends the linear measureable range of detecting cholesterol in solution. The thickness of seed layer has a significant influence on sensitivity for one dimensional nano ZnO cholesterol biosensor.
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U2 - 10.1088/1757-899X/131/1/012004
DO - 10.1088/1757-899X/131/1/012004
M3 - Conference article
AN - SCOPUS:84977275013
SN - 1757-8981
VL - 131
JO - IOP Conference Series: Materials Science and Engineering
JF - IOP Conference Series: Materials Science and Engineering
IS - 1
M1 - 012004
T2 - 4th International Conference on Manufacturing, Optimization, Industrial and Material Engineering, MOIME 2016
Y2 - 19 March 2016 through 20 March 2016
ER -