TY - JOUR
T1 - Synthesis of hollow, magnetic Fe/Ga-based oxide nanospheres using a bubble templating method in a microfluidic system
AU - Weng, Chen Hsun
AU - Huang, Chih Chia
AU - Yeh, Chen Sheng
AU - Lei, Huan Yao
AU - Lee, Gwo Bin
N1 - Funding Information:
Acknowledgments The authors gratefully acknowledge the financial support provided to this study by the National Science Council in Taiwan (NSC 96-2120-M-006-008). This work was also partially supported by the Ministry of Education, Taiwan, R.O.C. under the NCKU Project of Promoting Academic Excellence and Developing World Class Research Centers.
PY - 2009/12
Y1 - 2009/12
N2 - This paper describes a new approach to synthesize hollow nanospheres in a microfluidic system using air bubbles as templates. A new microfluidic system which integrates a micro-mixer, a micro-condenser channel, microvalves, a micro-heater, and a micro-temperature sensor, to form an automatic micro-reactor, is used to generate air bubbles that assist in the synthesis of hollow Fe/Ga-based oxide nanospheres. Experimental data show that Fe/Ga-based oxide nanoparticles with a diameter of 157 ± 26 nm can be successfully synthesized. The formation mechanism is that the seed nanoparticles are attaching themselves onto the bubbles to form a solid shell. The magnetic properties of the hollow Fe/Ga-based oxide nanospheres are also measured. This may be a promising platform to synthesize hollow nanoparticles for drug delivery applications.
AB - This paper describes a new approach to synthesize hollow nanospheres in a microfluidic system using air bubbles as templates. A new microfluidic system which integrates a micro-mixer, a micro-condenser channel, microvalves, a micro-heater, and a micro-temperature sensor, to form an automatic micro-reactor, is used to generate air bubbles that assist in the synthesis of hollow Fe/Ga-based oxide nanospheres. Experimental data show that Fe/Ga-based oxide nanoparticles with a diameter of 157 ± 26 nm can be successfully synthesized. The formation mechanism is that the seed nanoparticles are attaching themselves onto the bubbles to form a solid shell. The magnetic properties of the hollow Fe/Ga-based oxide nanospheres are also measured. This may be a promising platform to synthesize hollow nanoparticles for drug delivery applications.
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U2 - 10.1007/s10404-009-0442-5
DO - 10.1007/s10404-009-0442-5
M3 - Article
AN - SCOPUS:71249108219
SN - 1613-4982
VL - 7
SP - 841
EP - 848
JO - Microfluidics and Nanofluidics
JF - Microfluidics and Nanofluidics
IS - 6
ER -