The 83-kilodalton antigen of Borrelia burgdorferi which stimulates immunoglobulin M (IgM) and IgG responses in infected hosts is expressed by a chromosomal gene

R. B. Lefebvre, G. C. Perng, R. C. Johnson

研究成果: Article

23 引文 斯高帕斯(Scopus)

摘要

We report the cloning and characterization of a chromosomal gene from Borrelia burgdorferi expressing an 83-kilodalton protein antigen in Escherichia coli. The antigen reacted strongly with antisera from two human Lyme disease patients. The chromosomal gene was expressed in a 6.5-kilobase-pair ClaI fragment cloned in a variable-reading-frame plasmid vector.

原文English
頁(從 - 到)1673-1675
頁數3
期刊Journal of Clinical Microbiology
28
發行號7
DOIs
出版狀態Published - 1990

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

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