The alkaloids and other constituents from the root and stem of Aristolochia elegans

Li Shian Shi, Ping Chung Kuo, Yao Lung Tsai, Amooru Gangaiah Damu, Tian Shung Wu

研究成果: Article同行評審

41 引文 斯高帕斯(Scopus)

摘要

Two new aristolactams, aristolactam E (1) and aristolactam-AIIIa-6-O- β-D-glucoside (2), three novel benzoyl benzyltetrahydroisoquinoline ether N-oxide alkaloids, aristoquinoline A (3), aristoquinoline B (4), and aristoquinoline C (5), and a new biphenyl ether, aristogin F (6), together with 62 known compounds have been isolated from the root and stem of Aristolochia elegans Mast. The structures of the new natural products were established on the basis of spectral evidence. Some of the isolated compounds were examined for their antioxidative and antityrosinase activities. Occurrence of the isoquinolones, biphenyl ethers, and benzoyl benzyltetrahydroisoquinoline ether alkaloids in the same plant indicated the definite possibility of these metabolites as biotransformation intermediates of bisbenzyltetrahydroisoquinoline alkaloids. This can be useful to solve the catabolic process of bisbenzyltetrahydroisoquinoline alkaloids.

原文English
頁(從 - 到)439-446
頁數8
期刊Bioorganic and Medicinal Chemistry
12
發行號2
DOIs
出版狀態Published - 2004 1月 15

All Science Journal Classification (ASJC) codes

  • 生物化學
  • 分子醫學
  • 分子生物學
  • 藥學科學
  • 藥物發現
  • 臨床生物化學
  • 有機化學

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