The bakkenolides from the root of Petasites formosanus and their cytotoxicity

Tian Shung Wu, Mang San Kao, Pei Lin Wu, Ful Wen Lin, Li Shian Shi, Meei Jen Liou, Chia Ying Li

研究成果: Article同行評審

50 引文 斯高帕斯(Scopus)

摘要

Thirty-two new bakkenolides, bakkenolides-Db (1) - Dh (7), -Fa (8), -Fb (9), -I (10) - M (14), -Na (15), -Nb (16), -O (17) - T (22), -Ua (23),-Ub (24),-V (25) - X (27), -Ya (28),-Yb (29), -Za (30), -Zb (31) and -III (32), from the roots of Petasites formosanus together with thirty known compounds were isolated. The structures were characterized by spectral analysis. The locations, C-1 and/or C-9 of bakkenolide skeleton, of the substituents, such as acetoxy, isobutyroyloxy and isovaleroyloxy groups, can be determined by the chemical shifts of their signals and the H-1 and/H-9 in the 1H-NMR spectra. The cytotoxicity was also discussed.

原文English
頁(從 - 到)375-382
頁數8
期刊Chemical and Pharmaceutical Bulletin
47
發行號3
DOIs
出版狀態Published - 1999 3月

All Science Journal Classification (ASJC) codes

  • 化學 (全部)
  • 藥物發現

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