The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure

J. E. Looney; C. Ma; T. H. Leu; W. F. Flintoff; W. B. Troutman; J. L. Hamlin

doi:10.1128/mcb.8.12.5268

The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure

J. E. Looney, C. Ma, T. H. Leu, W. F. Flintoff, W. B. Troutman, J. L. Hamlin

藥理學科暨藥理學研究所

研究成果: Article › 同行評審

17 引文斯高帕斯（Scopus）

原文	English
頁（從 - 到）	5268-6279
頁數	1012
期刊	Molecular and Cellular Biology
卷	8
發行號	12
DOIs	https://doi.org/10.1128/mcb.8.12.5268
出版狀態	Published - 1988

All Science Journal Classification (ASJC) codes

分子生物學
細胞生物學

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10.1128/mcb.8.12.5268

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引用此

Looney, J. E., Ma, C., Leu, T. H., Flintoff, W. F., Troutman, W. B., & Hamlin, J. L. (1988). The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure. Molecular and Cellular Biology, 8(12), 5268-6279. https://doi.org/10.1128/mcb.8.12.5268

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title = "The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure",

author = "Looney, {J. E.} and C. Ma and Leu, {T. H.} and Flintoff, {W. F.} and Troutman, {W. B.} and Hamlin, {J. L.}",

year = "1988",

doi = "10.1128/mcb.8.12.5268",

language = "English",

volume = "8",

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Looney, JE, Ma, C, Leu, TH, Flintoff, WF, Troutman, WB & Hamlin, JL 1988, 'The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure', Molecular and Cellular Biology, 卷 8, 編號 12, 頁 5268-6279. https://doi.org/10.1128/mcb.8.12.5268

The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure. / Looney, J. E.; Ma, C.; Leu, T. H. 等.

於: Molecular and Cellular Biology, 卷 8, 編號 12, 1988, p. 5268-6279.

研究成果: Article › 同行評審

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T1 - The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure

AU - Looney, J. E.

AU - Ma, C.

AU - Leu, T. H.

AU - Flintoff, W. F.

AU - Troutman, W. B.

AU - Hamlin, J. L.

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AN - SCOPUS:0023685414

SN - 0270-7306

VL - 8

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EP - 6279

JO - Molecular and Cellular Biology

JF - Molecular and Cellular Biology

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Looney JE, Ma C, Leu TH, Flintoff WF, Troutman WB, Hamlin JL. The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure. Molecular and Cellular Biology. 1988;8(12):5268-6279. doi: 10.1128/mcb.8.12.5268