摘要
If acupuncture is able to prevent hypertrophy of the heart, it could therefore prevent the heart from overloading and thus prevent heart failure or sudden death. We therefore studied the effects of acupuncture on blood pressure and cardiac muscle cells. Rats with spontaneous hypertension were divided into three acupuncture treatment groups and one non-treatment group. The treatment groups were classified as sham acupoint, Yanglingquan (GB. 34) and Quchi (L1. 11) groups. The measurements recorded included changes in tail pressure, femoral arterial pressure, left ventricular weight (LVW), whole heart weight (WHW), body weight (BW), LVW/BW and WHW/BW ratios and the size of the cardiac muscle cells. The results showed that femoral arterial pressure of subjects which were needled on the selected points for 3 days dropped. Acupuncture at these two acupoints seemed to improve the condition of hypertension in a short period of time. Significant changes in the femoral arterial pressure were observed in all subjects when they were treated for 6 days. In the two acupoint groups, the LVW/BW and the WHW/BW ratios did not change significantly. Cardiac muscle cells reduced in size in the Yanglingquan (GB. 34) treatment groups. This indicates that the Yanglingquan (GB. 34) points not only can lower blood pressure, but also prevent hypertrophy of cardiac muscle cells in spontaneous hypertensive rats (SHR). Therefore, acupuncture could be a good treatment modality for hypertension and hypertrophy of the heart.
| 原文 | English |
|---|---|
| 頁（從 - 到） | 83-95 |
| 頁數 | 13 |
| 期刊 | Acupuncture and Electro-Therapeutics Research |
| 卷 | 29 |
| 發行號 | 1-2 |
| DOIs | |
| 出版狀態 | Published - 2004 一月 1 |
指紋
All Science Journal Classification (ASJC) codes
- Neuroscience(all)
- Complementary and alternative medicine
- Anesthesiology and Pain Medicine
引用此文
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The effects of acupuncture on cardiac muscle cells and blood pressure in spontaneous hypertensive rats. / Wu, Hung Chien; Lin, Jaung Geng; Chu, Chun-Hsien; Chang, Yung Hsien; Chang, Chung Gwo; Hsieh, Ching Liang; Tsai, Angela Hsin Chieh; Ueng, Kwo Chang; Kuo, Wei Wen; Lin, James A.; Liu, Jer Yuh; Huang, Chih Yang.
於: Acupuncture and Electro-Therapeutics Research, 卷 29, 編號 1-2, 01.01.2004, p. 83-95.研究成果: Article
TY - JOUR
T1 - The effects of acupuncture on cardiac muscle cells and blood pressure in spontaneous hypertensive rats
AU - Wu, Hung Chien
AU - Lin, Jaung Geng
AU - Chu, Chun-Hsien
AU - Chang, Yung Hsien
AU - Chang, Chung Gwo
AU - Hsieh, Ching Liang
AU - Tsai, Angela Hsin Chieh
AU - Ueng, Kwo Chang
AU - Kuo, Wei Wen
AU - Lin, James A.
AU - Liu, Jer Yuh
AU - Huang, Chih Yang
PY - 2004/1/1
Y1 - 2004/1/1
N2 - If acupuncture is able to prevent hypertrophy of the heart, it could therefore prevent the heart from overloading and thus prevent heart failure or sudden death. We therefore studied the effects of acupuncture on blood pressure and cardiac muscle cells. Rats with spontaneous hypertension were divided into three acupuncture treatment groups and one non-treatment group. The treatment groups were classified as sham acupoint, Yanglingquan (GB. 34) and Quchi (L1. 11) groups. The measurements recorded included changes in tail pressure, femoral arterial pressure, left ventricular weight (LVW), whole heart weight (WHW), body weight (BW), LVW/BW and WHW/BW ratios and the size of the cardiac muscle cells. The results showed that femoral arterial pressure of subjects which were needled on the selected points for 3 days dropped. Acupuncture at these two acupoints seemed to improve the condition of hypertension in a short period of time. Significant changes in the femoral arterial pressure were observed in all subjects when they were treated for 6 days. In the two acupoint groups, the LVW/BW and the WHW/BW ratios did not change significantly. Cardiac muscle cells reduced in size in the Yanglingquan (GB. 34) treatment groups. This indicates that the Yanglingquan (GB. 34) points not only can lower blood pressure, but also prevent hypertrophy of cardiac muscle cells in spontaneous hypertensive rats (SHR). Therefore, acupuncture could be a good treatment modality for hypertension and hypertrophy of the heart.
AB - If acupuncture is able to prevent hypertrophy of the heart, it could therefore prevent the heart from overloading and thus prevent heart failure or sudden death. We therefore studied the effects of acupuncture on blood pressure and cardiac muscle cells. Rats with spontaneous hypertension were divided into three acupuncture treatment groups and one non-treatment group. The treatment groups were classified as sham acupoint, Yanglingquan (GB. 34) and Quchi (L1. 11) groups. The measurements recorded included changes in tail pressure, femoral arterial pressure, left ventricular weight (LVW), whole heart weight (WHW), body weight (BW), LVW/BW and WHW/BW ratios and the size of the cardiac muscle cells. The results showed that femoral arterial pressure of subjects which were needled on the selected points for 3 days dropped. Acupuncture at these two acupoints seemed to improve the condition of hypertension in a short period of time. Significant changes in the femoral arterial pressure were observed in all subjects when they were treated for 6 days. In the two acupoint groups, the LVW/BW and the WHW/BW ratios did not change significantly. Cardiac muscle cells reduced in size in the Yanglingquan (GB. 34) treatment groups. This indicates that the Yanglingquan (GB. 34) points not only can lower blood pressure, but also prevent hypertrophy of cardiac muscle cells in spontaneous hypertensive rats (SHR). Therefore, acupuncture could be a good treatment modality for hypertension and hypertrophy of the heart.
UR - http://www.scopus.com/inward/record.url?scp=4143087959&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4143087959&partnerID=8YFLogxK
U2 - 10.3727/036012904815901515
DO - 10.3727/036012904815901515
M3 - Article
C2 - 15382791
AN - SCOPUS:4143087959
VL - 29
SP - 83
EP - 95
JO - Acupuncture and Electro-Therapeutics Research
JF - Acupuncture and Electro-Therapeutics Research
SN - 0360-1293
IS - 1-2
ER -