The facile reversed-phase HPLC resolution of tetrahydrofurofuran nucleus lignans in traditional Chinese medicine: Quantitative analysis of asarinin and sesamin in Asari radix

Chao Chiun Wang, Shushi Chen, Tian Shung Wu

研究成果: Article同行評審

10 引文 斯高帕斯(Scopus)

摘要

Eight tetrahydrofurofuran nucleus lignans: syringaresinol, epi-syringaresinol, lirioresinol-B dimethyl ether, xanthoxylol, phillygenin, fargesin, sesamin and asarinin are separated on a C18 column in the reversed-phase mode. These lignans are plant products formed primarily by the carbon-carbon coupling of derivatives of cinnamyl alcohol units, in which the two units may be linked by an oxygen bridge to form a tetrahydrofurofuran nucleus and are found to be highly similar in structure. However, these lignans can be baseline resolved under gradient elution in less than 25 minutes. The resolution also can be optimized through altering the flow rate in an isocratic elution. This method is proven to be facile and reliable in routine quantitative analysis of ingredients such as asarinin and sesamin in traditional Chinese medicine Asarum sieboldii. The corresponding recoveries (%) were found to be 95.65 and 96.14, respectively.

原文English
頁(從 - 到)261-266
頁數6
期刊Journal of the Chinese Chemical Society
50
發行號2
DOIs
出版狀態Published - 2003 一月 1

All Science Journal Classification (ASJC) codes

  • 化學 (全部)

指紋

深入研究「The facile reversed-phase HPLC resolution of tetrahydrofurofuran nucleus lignans in traditional Chinese medicine: Quantitative analysis of asarinin and sesamin in Asari radix」主題。共同形成了獨特的指紋。

引用此