TY - JOUR
T1 - The first isolation of an acridone alkaloid from poncirus trifoliata
AU - Wu, Tian Shung
AU - Jin Cheng, Ru
AU - Huang, Shiow Chyn
AU - Furukawa, Hiroshi
PY - 1986/1/1
Y1 - 1986/1/1
N2 - Poncirus trifoliata (L.) Raf. (Rutaceae) is the original plant of the traditional Chinese medicine “Gou Ju,” which has been used for treating pain, stomach ache, hysteroptosis, stagnant blood, and as a detoxicant of wine poisoning (1). The presence of an essential oil, coumarins, and flavonoids in this plant has been reported (2-9). However, no alkaloidal component has been detected in this plant. In the course of our studies on the isolation of the acridone alkaloids in the Rutaceae, we have reinvestigated the constituents of this plant and identified the acridone alkaloid, 5-hydroxynoracronycine, in the root bark. This is the first example of the isolation of an acridone alkaloid from the genus Poncirus. Coumarins, poncitrin (dentatin), nordentatin, and marmesin, were also identified.
AB - Poncirus trifoliata (L.) Raf. (Rutaceae) is the original plant of the traditional Chinese medicine “Gou Ju,” which has been used for treating pain, stomach ache, hysteroptosis, stagnant blood, and as a detoxicant of wine poisoning (1). The presence of an essential oil, coumarins, and flavonoids in this plant has been reported (2-9). However, no alkaloidal component has been detected in this plant. In the course of our studies on the isolation of the acridone alkaloids in the Rutaceae, we have reinvestigated the constituents of this plant and identified the acridone alkaloid, 5-hydroxynoracronycine, in the root bark. This is the first example of the isolation of an acridone alkaloid from the genus Poncirus. Coumarins, poncitrin (dentatin), nordentatin, and marmesin, were also identified.
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U2 - 10.1021/np50048a044
DO - 10.1021/np50048a044
M3 - Article
AN - SCOPUS:33845375445
VL - 49
SP - 1154
EP - 1155
JO - Journal of Natural Products
JF - Journal of Natural Products
SN - 0163-3864
IS - 6
ER -