The rising trend of sexually transmitted infections among HIV-infected persons: A population-based cohort study in taiwan, 2000 through 2010

Yen Chin Chen, Hsiao Ying Liu, Chung Yi Li, Nan Yao Lee, Chia Wen Li, Wen Chien Ko, Nai Ying Ko

研究成果: Article同行評審

7 引文 斯高帕斯(Scopus)

摘要

Objective: Positive prevention interventions for patients living with the HIV include the early detection and treatment of sexually transmitted infections (STIs). This study aimed to determine the incidence of selected STIs, including syphilis, genital warts, gonorrhea, chlamydial infection, and trichomoniasis, in a population- based cohort of individuals living with HIV. Methods: Clinical data from 2000 to 2010 were obtained from the Taiwan National Health Insurance Research Database identified 15,123 patients with HIV infection. The incidence rates were standardized by age and sex using the direct method that was based on the 2000 World Health Organization world standard population. Results: The overall rate ratio of STI episodes significantly increased [rate ratio: 34.0, 95% confidence interval (CI): 24.3 to 47.6, P<0.01]. After an HIV diagnosis, 15.9% of patients with HIV had at least 1 of these 5 STIs. An incidence rate of 503.0 STI episodes/10,000 person-years (PYs) (95% CI: 487.1 to 519.5) was detected during the 11-year follow-up period. The most common STIs after an HIV diagnosis were syphilis (381.9 episodes/10,000 PYs; 95% CI: 368.0 to 396.3), followed by genital warts (138.9 episodes/ 10,000 PYs; 95% CI: 130.6 to 147.6). The incidence of STIs varied significantly according to gender. In women, the annual incidence of STIs remained stable. However, the annual incidence of syphilis, genital warts, and chlamydial infection increased in young men. Conclusions: An increase in STIs among HIV-positive persons highlights the need to identify the causal factors of these coinfections. Routine STI screenings and early preventive interventions against STIs in HIV-infected persons are crucial.

原文English
頁(從 - 到)432-438
頁數7
期刊Journal of Acquired Immune Deficiency Syndromes
68
發行號4
DOIs
出版狀態Published - 2015 四月 1

All Science Journal Classification (ASJC) codes

  • 傳染性疾病
  • 藥學(醫學)

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