Tough and antifouling polyampholyte hydrogels via photopolymerization of equivalent ionic monomers with poly(ethylene glycol) diacrylate

Po Hsin Wang, Chen Hsueh Lin, Ten Chin Wen

研究成果: Article同行評審

6 引文 斯高帕斯(Scopus)

摘要

Tough and antifouling polyampholyte hydrogels can be prepared through the photopolymerization of the equivalent [2-(acryloyloxy)ethyl]trimethylammonium chloride([TMA][Cl]) and 2-acrylamido-2-methyl-1-propanesulfonic acid sodium([Na][AMPS]) with poly(ethylene glycol) diacrylate (PEGDA). Fourier-transform infrared spectra evidenced the linkage between PEGDA and TMA/AMPS. With the different ratios of TMA to AMPS, the copolymers presented the different morphological surfaces and also exhibited different swelling ratios. Among all copolymers, the equivalent ionic hydrogel A50S50 ([TMA] = [AMPS]) demonstrated the highest mechanical properties with toughness of 230.98 kJm-1 and compressive strain of 100%. Hydrogel A50S50 also presented the optimal protein fouling ability for both Bovine-serum-albumin (BSA, anionic protein) and Lysozyme (LYZ, cationic protein). On the other hand, A50S50 also showed the biocompatibility (low cytotoxicity and hemolytic ratio), being certified by MTT assay and hemolysis test. A polyampholyte A50S50 with equivalent ionic monomers possessed both tough and antifouling properties, being highly promising for load-bearing and antifouling biomedical applications.

原文English
頁(從 - 到)101-106
頁數6
期刊Journal of the Taiwan Institute of Chemical Engineers
113
DOIs
出版狀態Published - 2020 8月

All Science Journal Classification (ASJC) codes

  • 一般化學
  • 一般化學工程

指紋

深入研究「Tough and antifouling polyampholyte hydrogels via photopolymerization of equivalent ionic monomers with poly(ethylene glycol) diacrylate」主題。共同形成了獨特的指紋。

引用此