Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients—When Intravesical Botox Injection or Urethral Botox Injection Are Indicated

Po Cheng Chen, Kau Han Lee, Wei Chia Lee, Ting Chun Yeh, Yuh Chen Kuo, Bing Juin Chiang, Chun Hou Liao, En Meng, Yao Lin Kao, Yung Chin Lee, Hann Chorng Kuo

研究成果: Review article同行評審

3 引文 斯高帕斯(Scopus)

摘要

Lower urinary tract symptoms (LUTS), such as urgency, urinary incontinence, and/or difficulty voiding, hamper the quality of life (QoL) of patients with spinal cord injury (SCI). If not managed adequately, urological complications, such as urinary tract infection or renal function deterioration, may further deteriorate the patient’s QoL. Botulinum toxin A (BoNT-A) injection within the detrusor muscle or urethral sphincter yields satisfactory therapeutic effects for treating urinary incontinence or facilitating efficient voiding; however, adverse effects inevitably follow its therapeutic efficacy. It is important to weigh the merits and demerits of BoNT-A injection for LUTS and provide an optimal management strategy for SCI patients. This paper summarizes different aspects of the application of BoNT-A injection for lower urinary tract dysfunctions in SCI patients and provides an overview of the benefits and drawbacks of this treatment.

原文English
文章編號288
期刊Toxins
15
發行號4
DOIs
出版狀態Published - 2023 4月

All Science Journal Classification (ASJC) codes

  • 毒理學
  • 健康、毒理學和誘變

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