Typhoid fever complicated by multiple organ involvement: Report of two cases

Guan Cheng Huang, Chia-Ming Chang, Wen-Chien Ko, Yu Lun Huang, Yin Ching Chuang

研究成果: Article同行評審

5 引文 斯高帕斯(Scopus)


Typhoid fever complicated by multiple organ involvement has been rarely mentioned in the literature. We reported two cases of typhoid fever with several unusual manifestations, including acute renal failure, acute hepatitis, acute pancreatitis, disseminated intravascular coagulation, and lower gastrointestinal bleeding. A renal biopsy in the first case showed no pathological change. Bone marrow biopsy showed focal necrosis of matrix, which might have been due to severe illness. A liver biopsy in the second case showed a predominantly histiocytic proliferation with occasional neutrophilic infiltration in the portal areas and hepatic sinusoids. Focal necrosis, bile duct injury, and multiple eosinophilic bodies were also noted. After appropriate antimicrobial therapy, both patients recovered without any sequelae. The potential of multiple organ involvement is highlighted in typhoid fever, which, on rare occasions, may occur simultaneously in the same patient.

期刊Journal of Infection
出版狀態Published - 2005 八月 1

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

指紋 深入研究「Typhoid fever complicated by multiple organ involvement: Report of two cases」主題。共同形成了獨特的指紋。