Unilateral malignant optic glioma following glioblastoma multiforme in the young: A case report and literature review

Chia Ying Lin, Hsiu Mei Huang

研究成果: Review article同行評審

3 引文 斯高帕斯(Scopus)

摘要

Background: Malignant optic gliomas are rare, but they rapidly become lethal visual pathway tumors. We present the clinical course, treatment, and prognosis of a case of unilateral malignant optic glioma in a young man with a history of brain glioblastoma multiforme (GBM). Case presentation: A 21-year-old man, who had GBM 7 years ago complained of a transient shadow in his vision and presented with normal visual acuity but optic disc edema and an enlarged blind spot in the right eye (oculus dexter, OD). Magnetic resonance imaging (MRI) showed a right intraorbital optic nerve tumor without a brain lesion. Chiasm involvement and severe vision deterioration occurred 3 months later. A biopsy of the right optic nerve revealed glioblastoma. Concurrent chemoradiotherapy (CCRT) prevented involvement of the fellow eye 1 year after symptom onset. Conclusion: This report demonstrated that a regular ocular exam should be recommended for several years after GBM. In young healthy patients who are able to undergo chemotherapy and radiotherapy, visual function in the fellow eye can be preserved.

原文English
文章編號21
期刊BMC Ophthalmology
17
發行號1
DOIs
出版狀態Published - 2017 三月 11

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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