Upconversion Nanodevice-Assisted Healthy Molecular Photocorrection

Kamaljit Kaur, Pulkit Bindra, Sanjit Mondal, Wei Peng Li, Sandeep Sharma, Bandana Kumari Sahu, Boddu S. Naidu, Chen Sheng Yeh, Ujjal K. Gautam, Vijayakumar Shanmugam

研究成果: Article同行評審

摘要

Mushrooms are rich in ergosterol, a precursor of ergocalciferol, which is a type of vitamin D2. The conversion of ergosterol to ergocalciferol takes place in the presence of UV radiation by the cleavage of the "B-ring"in the ergosterol. As the UV radiation cannot penetrate deep into the tissue, only minimal increase occurs in sunlight. In this study, upconversion nanoparticles with the property to convert deep-penetrating near-infrared radiation to UV radiation have been cast into a disk to use sunlight and emit UV radiation for vitamin D conversion. An engineered upconversion nanoparticle (UCNP) disk with maximum particles and limited clusters demonstrates ∼2.5 times enhanced vitamin D2 conversion.

原文English
頁(從 - 到)291-298
頁數8
期刊ACS Biomaterials Science and Engineering
7
發行號1
DOIs
出版狀態Published - 2021 一月 11

All Science Journal Classification (ASJC) codes

  • 生物材料
  • 生物醫學工程

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