Using clinical registries, administrative data and electronic medical records to improve medication safety and effectiveness in dementia

Jenni Ilomäki, Edward Chia Cheng Lai, J. Simon Bell

研究成果: Article同行評審

2 引文 斯高帕斯(Scopus)

摘要

Purpose of reviewClinical registries, routinely collected administrative data and electronic medical records (EMRs) provide new opportunities to investigate medication safety and effectiveness. This review outlines the strengths and limitations of these data, and highlights recent research related to safe and effective medication use in dementia.Recent findingsClinical registries, administrative data and EMRs facilitate observational research among people often excluded from randomized controlled trials (RCTs). Larger sample sizes and longer follow-up times permit research into less common adverse events not apparent in RCTs. The validity of diagnoses recorded in administrative data and EMRs remains variable, although positive predictive values are typically high and sensitivity is low. Dispensing records are a rich source of data for estimating medication exposure. Recent research has investigated medications and prescribing patterns as risk factors for incident dementia, strategies to alleviate behavioural symptoms and the management of comorbidity. Common study protocols and common data models are examples of distributed network approaches increasingly used to conduct large and generalizable multi-database studies across different countries.SummaryGreater availability of electronic health data provides important opportunities to address evidence-practice gaps in relation to medication use and safety in people with dementia.

原文English
頁(從 - 到)163-169
頁數7
期刊Current Opinion in Psychiatry
33
發行號2
DOIs
出版狀態Published - 2020 三月 1

All Science Journal Classification (ASJC) codes

  • 精神病學和心理健康

指紋

深入研究「Using clinical registries, administrative data and electronic medical records to improve medication safety and effectiveness in dementia」主題。共同形成了獨特的指紋。

引用此