Validation of the World Health Organization quality of life instrument in patients with HIV infection

C. T. Fang, P. C. Hsiung, C. F. Yu, M. Y. Chen, Jung Der Wang

研究成果: Article同行評審

76 引文 斯高帕斯(Scopus)

摘要

We studied the reliability and validity of the World Health Organization quality of life (WHOQOL) assessment instrument in patients with human immunodeficiency virus (HIV) infection. WHOQOL-BREF was used to assess 136 HIV-infected outpatients. The results were analyzed and compared with data from 213 healthy persons. The Cronbach's α for internal consistency ranged from 0.74 to 0.85 across domains in HIV-infected patients. The test-retest reliability ranged from 0.64 to 0.79 across domains at average 4-week retest interval. Factor analysis identified four major factors: social, psychological, environment, and physical, consistent with the four domains of the instrument. The scores of all four domains correlated positively with self-evaluated health status and happiness (r range: 0.52-0.60 and 0.55-0.73 across domains, respectively), and correlated negatively with the number and severity of symptoms (r range: -0.40 to -0.47 and -0.41 to -0.52, respectively). The scores of physical, psychological and social domains, but not the environment domain, discriminated between healthy persons and HIV-infected patients (all p < 0.01). We conclude that the WHOQOL-BREF can be a useful quality-of-life instrument in patients with HIV infection.

原文English
頁(從 - 到)753-762
頁數10
期刊Quality of Life Research
11
發行號8
DOIs
出版狀態Published - 2002 十二月

All Science Journal Classification (ASJC) codes

  • 公共衛生、環境和職業健康

指紋

深入研究「Validation of the World Health Organization quality of life instrument in patients with HIV infection」主題。共同形成了獨特的指紋。

引用此