Velocity measurement in microchannels with a laser confocal microscope and particle linear image velocimetry

Shih Hui Chao, Mark R. Holl, John H. Koschwanez, Rob H. Carlson, Ling Sheng Jang, Deirdre R. Meldrum

研究成果: Article同行評審

10 引文 斯高帕斯(Scopus)


Particle linear image velocimetry (PLIV), a novel velocity measurement method for microfluidic characterization, is reported. The method records a series of one-dimensional images that represent the trace of particles in the flow across a one-dimensional imager. Linear imaging results in a faster frame rate than planar imaging, allowing observations at larger magnifications, or the measurement of faster flow in real-time than comparable techniques. In contrast to particle image velocimetry (PIV), PLIV captures fast flow dynamics and does not require high-speed cameras or shutters. Furthermore, PLIV is adaptable to multiple linear imager formats and, as one example, can use laser scanning confocal microscopes (LSCMs) that acquire images slowly, but with high optical sectioning resolutions. A higher spatial resolution can be obtained for flows where the in-plane velocity gradient in the direction of the optical path (z direction) is important. The PLIV algorithm is fully described and its utility is demonstrated by the measurement of: a steady Poiseuille flow with 1-μm spatial resolution in a microfluidic environment; dynamic measurement of transient flows with 250-ms temporal resolution; and the simultaneous calculation of particle dimension statistics.

頁(從 - 到)155-160
期刊Microfluidics and Nanofluidics
出版狀態Published - 2005 五月

All Science Journal Classification (ASJC) codes

  • 電子、光磁材料
  • 凝聚態物理學
  • 材料化學


深入研究「Velocity measurement in microchannels with a laser confocal microscope and particle linear image velocimetry」主題。共同形成了獨特的指紋。