Zika Virus Dependence on Host Hsp70 Provides a Protective Strategy against Infection and Disease

Shuhei Taguwa; Ming Te Yeh; T. Kelly Rainbolt; Arabinda Nayak; Hao Shao; Jason E. Gestwicki; Raul Andino; Judith Frydman

doi:10.1016/j.celrep.2018.12.095

Zika Virus Dependence on Host Hsp70 Provides a Protective Strategy against Infection and Disease

Shuhei Taguwa
, Ming Te Yeh
, T. Kelly Rainbolt
, Arabinda Nayak
, Hao Shao
, Jason E. Gestwicki
, Raul Andino
, Judith Frydman

微生物學科暨微生物及免疫學研究所

研究成果: Article › 同行評審

90 引文斯高帕斯（Scopus）

摘要

Hsp70 inhibitors effectively block Zika virus replication in both human and mosquito cells, without the emergence of drug resistance, and protect mice from lethal ZIKV infection, demonstrating their potential for treatment and prevention of ZIKV disease.

原文	English
頁（從 - 到）	906-920.e3
期刊	Cell Reports
卷	26
發行號	4
DOIs	https://doi.org/10.1016/j.celrep.2018.12.095
出版狀態	Published - 2019 1月 22

UN SDG

此研究成果有助於以下永續發展目標

SDG 3 良好的健康和福祉

All Science Journal Classification (ASJC) codes

一般生物化學，遺傳學和分子生物學

存取文件

10.1016/j.celrep.2018.12.095

其它文件與鏈接

引用此

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AU - Shao, Hao

AU - Gestwicki, Jason E.

AU - Andino, Raul

AU - Frydman, Judith

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