Painful Diabetic Neuropathy Functional Performance and Quality of Life among Type II Diabetes Mellitus Patients in Indonesia

摘要

Background: Type 2 Diabetes mellitus (T2DM) patients may experience painful diabetic neuropathy one of the symptoms of distal symmetric polyneuropathy (DSPN) While pain is a highly unpleasant symptom affecting and disrupting people’s life Painful Diabetic Neuropathy (PDN) is overlooked which may impact patient’s functional performance and quality of life There is limited information regarding the relationships of PDN functional performance and quality of life among patients with T2DM in Indonesia Purpose: The purpose of the study was to investigate the relationships among demographic factors health characteristics painful diabetic neuropathy functional performance and quality of life among patients with T2DM in Indonesia Method: This study uses a cross-sectional design The participants were T2DM patients with an abnormal monofilament test and able to communicate using the Indonesian language Self-reported Leeds Assessment of Neuropathic Signs and Symptoms (s-LANSS) was used to assess neuropathic pain Short-Form 36-Item Health Survey (SF-36) was used to measure functional performance and quality of life Algorithm software was used to calculate the scoring of functional performance and index of quality of life separately Results: A total of 200 patients with T2DM participated in this study The mean age of the participants was 59 77 (SD=8 45) years old ranging from 40 to 79 years old 53% were male 73 5 % had high school or higher education level 91% were employed and 59 5% had low-income status The mean score of Body Mass Index (BMI) was 23 60 (SD=2 68) The mean duration diagnosed with Diabetes Mellitus (DM) was 6 68 (SD=4 56) and the median was six years (ranging from 4 months - 25 years) Eighty-two percent of the participants took oral medicine treatment only 11 5% got insulin treatment and 16% got the combination of oral and insulin treatment There were 40% of the participants a smoker Three-quarters of the subjects experienced pain above the ankle and 79% had painful discomfort Hierarchical multiple regressions revealed age occupation DM duration the area of worst pain and painful neuropathic discomfort were predictors of functional performance with R2=0 26 Also occupation income level BMI treatment regimens and area of worst pain were predictors of quality of life with R2=0 23 Conclusions: Neuropathic pain is related to functional performance and quality of life among T2DM patients Therefore performing early screening to detect painful diabetic neuropathy and its impact on functional performance and quality of life is needed Keywords: Type 2 diabetes mellitus painful diabetic neuropathy functional performance and quality of life

獎項日期	2017 8月 17
原文	English
監督員	Yu-Yun Hsu (Supervisor)